Introduction: The psoriasis is one of the inflammatory dermatoses with unknown\netiology, with chronic evolution having episodic appearance and disappearance.\nIts prevalence in HIV patients varied from 2% to 5% in most of\nthe times. Objective of this study was to describe the demographic, clinical\nand therapeutic characteristics of psoriasis patients infected with HIV. Methods:\nIt is a descriptive retrospective study done from January 2003 to December\n2013 based on the information from the hospital card of hospitalized\npatients and outpatients taken care in the department of Dermatology-STD\nfor psoriasis at the University hospital center in Donka Conakry. We included\nall the cases of psoriasis associated with HIV infection diagnosed from clinical\nand paraclinical elements. Results: We recorded 23 (24.73%) cases of psoriasis\nassociated with HIV infection among 93 patients observed for psoriasis in\nwhich there are 4 cases of psoriasis vulgaris, 10 cases of erythrodermic psoriasis\nand 9 cases of arthropathic form among these numbers. We had 7 women\nand 16 men. The medium age of our patients was 44.5 �± 12 years 27 - 62\nyears. The delayed duration time of consultation varied from 30 to more than\n180 days. The psoriasis was the circumstance of the discovery of the HIV infection\namong 55% of cases. The pruritus was the functional sign which is the\nmost frequent in 20 cases among 23 cases and 71.4% of cases were accompanied\nwith pain. Family history was found in 7.10% of cases. Anxiety was the\ndominant factor cause in 42% and the infection 38%. The cutaneous alteration\nwas noted in all patients; 92.9% of patients had nails alteration and intertrigineous\nassociation in 78.6% of cases. The clinical forms found were psoriasis vulgaris 4/23 cases, arthropathic psoriasis 9/23 cases, erythrodermic psoriasis\n10/23. More than half (13/23) cases of our patients were diagnosed stage III of\nthe classification of WHO. The complicated forms like erythrodermic and\narthropathic psoriasis were frequent in patients whose total CD4 < 350 cells/�¼l\nabout 65%. The most frequently encountered co-morbidity was tuberculosis\n(9 cases). The use of traditional therapeutic means was noted in 50% of cases.\nThe local treatment was based on dermocorticoid and keratolylic drugs. The\ngeneral treatment received by all patients was antiretroviral medication and\nMethotrexate. Discussion: Our results are of course not representing all the\ncases of psoriasis in Guinea but it gives us an idea of the importance of HIV\nand psoriasis association and the influence of immunodepression inducted by\nHIV during the evolution of psoriasis. The demographic, clinical and therapeutic\ncharacteristics described in our patients were near those reported by\nmore authors. Conclusion: HIV-associated psoriasis does not appear to be\nfamilial. Serious clinical forms occur in highly immunocompromised patients.
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